Levitra is one of the best drugs used to treat erectile dysfunction. It is a brand-name medicine that contains vardenafil, a PDE5 inhibitor. Today, it is possible to find a range of generic versions of Levitra, and many people ask if they are of the same quality as the brand-name drug or it is better to purchase an original medication.
Generic Levitra is a drug that also contains vardenafil, and it provides the same effects as the original brand-name medication. The production of generic version of Levitra became possible when the patent for Levitra expired.
The manufacturers of generic versions do not have to pay all of the expenses that are usually covered by the manufacturer of the original drugs, such as certain clinical trials, obtaining approvals, marketing and advertising campaign, and others. That is why generic Levitra is available at lower prices while offering the same therapeutic effects.
Mechanism of Action
Vardenafil works like other PDE5 inhibitors, such as tadalafil (Cialis) and sildenafil (Viagra). An erection occurs thanks to blood that fills out the penis. It is possible because of the blood vessels increased in size. Simultaneously, the blood vessels responsible for carrying blood away decrease in size preventing the blood from leaving the penis. The engorgement of the penis is initialized by sexual stimulation, which stimulates the production of nitric oxide. It activates guanylate cyclase, a lyase enzyme, to release cGMP, which is responsible for the size of the blood vessels.
Vardenafil works by preventing phosphodiesterase-5 (PDE-5), an enzyme, from decreasing the level of cGMP, so that cGMP remains longer.
The daily recommended dose of vardenafil is 10mg. It works for most men; however, the dosage may be adjusted (increased up to 20mg or decreased to 5mg) depending on how a man responds to the drug, his health conditions, other medicines used, the presence of side effects, and other factors.
The recommended starting dosage for men over 65 years old is 5mg. The maximum daily dosage of the active ingredient is 20mg. No more than one dosage should be taken per day.
Warning and Precautions
If generic Levitra causes an allergic reaction, it should not be taken anymore. Before using a drug, go to your healthcare provider and check if there are any contraindications not allowing you to use generic Levitra. Particularly, your doctor will need to take to attention all of the health problems that you may have, including:
- Heart problems;
- Stroke/heart attack within the last several months;
- Kidney/liver disease;
- Blood disorder;
- Abnormal blood pressure;
- Abnormal penis conditions;
- History of priapism;
- Active stomach ulcers;
- Bleeding disorder;
- Eye problems.
It is necessary to avoid consuming grapefruit/grapefruit juice while generic Levitra is being used because this may increase the risk of side effects. Using marijuana or alcohol along with the medicine may make you dizzy.
Most commonly, vardenafil causes the following side effects:
- Flu-like symptoms;
- Facial flushing;
- Stomach upset;
Serious side effects that require urgent medical help:
- Chest pain;
- Serious vision problems;
- Serious hearing problems;
- Low blood pressure;
Generic Levitra should not be used with certain medications and supplements due to interaction.
The elimination of the active ingredient from the body cannot normally be conducted if it is combined with the following medicines:
Generic Levitra reduces the concentration of certain medications in blood, which decreases their effectiveness. Particularly, it should not be taken along with the following meds:
Vardenafil along with nitrates may lead to chest pain and a significant decrease in blood pressure. Generic Levitra also decreases effects of alpha-blocking medicines, such as terazosin (Hytrin).
It is strongly recommended to consult a healthcare provider before combining Vardenafil with any prescription or non-prescription drug.